Cellular Resp.

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Cellular respiration is a controlled sequence of steps in a series of biochemical pathways. The goal is to harvest energy from glucose as ATP, energy the cell can use to do its various functions. This is oversimplified, but it should work. 

Check it out!

A simplified overview of cellular respiration.

Why a controlled sequence of steps? http://www.accessexcellence.org/AB/GG/cell_Oxid.html

Look here http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/C/CellularRespiration.html

or here for an overall view of cellular respiration.

Do you feel like you need to more about the mitochondrion? Look here http://www.cytochemistry.net/Cell-biology/mitoch3.htm

The following two sites were the ones used in lecture:

Animation of ETS.

Animation of ATP synthesis in the mitochondrion.

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Another animation is found here. 

Is fermentation ever useful to humans? Of course! See here.

Just oxidative phosphorylation you say?

Questions & Things to Note

What is cellular respiration? What are the steps (4 not 3) in cellular respiration? Where does each step occur? Why is glycolysis said to be anaerobic? Does pyruvate enter the Kreb's cycle? Explain.

Where are the three areas that glycolysis is controlled? Where do other monosaccharides enter the glycolytic pathway? 

You will recognize some of the intermediates in the Citric Acid Cycle. Where have you seen a-ketoglutaric acid? How many ATP is each NADH worth? When is the NADH converted to ATP? What about FADH2 and GTP?

What happens under anaerobic conditions? 

What happens if you are not beginning with glucose? Where does a fatty acid enter the catabolic process? An amino acid?

Further study: How are carbohydrates converted into fat? See this page.

Or this short explanation of gluconeogenesis and ketogenesis.

Explanation of diabetic ketoacidosis.

Here is a link to the pages with the animations shown in class. 

 

© 2005 STCC Foundation Press
Author:  Michele Nash