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Due: Thursday November 5th 2009

Karyotyping exercise

 

1. Online Karyotyping exercise

Visit the following website:

http://biology.wsc.ma.edu/hoagland/Chicopee/chromosomes.htm

Read the background information there, and then complete the assignment at the bottom of the page (described in the last sentence at the bottom of the page).

2. Complete a full karyotype

You will be assigned one karyotype file--your job is to complete the karyotype and determine the chromosome composition and if there is a chromosome anomaly.  Your karyotype will be from one of the following:

normal female
normal male
Turners syndrome female
Klinefelters male
Downs syndrome female
Patau syndrome male
Edwards syndrome male

Open the file that  matches your assigned letter below.  It will contain a page with a chromosome spread and a page with a blank Karyotype sheet.  Drag and drop the chromosomes onto the correct spot on the karyotype.  Determine if there is an abnormal number of chromosomes; if so record the name of the disorder on the sheet.  Otherwise indicate "normal female" or "normal male".  Also record the chromosome designation on the sheet.  Use the Resources below to help. 

Click on the links below to open your file. 

Karyotype A (Lorraine)

Karyotype B (Natalie)

Karyotype C (Ewelina)

Karyotype D (Kelsey)

Karyotype E (Denise)

Karyotype F (Lisa)

Karyotype G (Kevin)

Karyotype H (Alex)

Karyotype I (John)

Karyotype J (James)

 

Resources:

Use these sample karyotypes to help identify your chromosomes and place them in the correct location.  Sample karyotype 1 has them arranged on a karyotype sheet like the one I am having you use. 

Sample complete karyotype 1

Sample complete karyotypes 2 & 3

*Helpful hint: remember that chromosomes from different chromosome spreads will look a little different--they can be bent in different ways for example.

 

This has written descriptions of all the chromosomes, which may help you to properly place them. 

Chromosome descriptions

 

What to hand in:

bulletthe completed sheet from Step 1
bulletthe completed karyotype from Step 2